HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis.

HIV-1 Nef down-regulates the hemochromatosis protein HFE, manipulating cellular iron homeostasis.

The multifunctional Nef protein of HIV-1 is important for the progression to AIDS. One action of Nef is to down-regulate surface MHC I molecules, helping infected cells to evade immunity. We found that Nef also down-regulates the macrophage-expressed MHC 1b protein HFE, which regulates iron homeosta...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Drakesmith, H, Chen, N, Ledermann, H, Screaton, G, Townsend, A, Xu, X
Формат:	Journal article
Хэл сонгох:	English
Хэвлэсэн:	2005

Ижил төстэй зүйлс

The hemochromatosis protein HFE inhibits iron export from macrophages.
-н: Drakesmith, H, зэрэг
Хэвлэсэн: (2002)

Possible roles of the hereditary hemochromatosis protein, HFE, in regulating cellular iron homeostasis
-н: CAROLINE A ENNS
Хэвлэсэн: (2006-01-01)

HFE Related Hemochromatosis: Uncovering the Inextricable Link between Iron Homeostasis and the Immunological System
-н: Graça Porto, зэрэг
Хэвлэсэн: (2019-08-01)

Diabetes in HFE Hemochromatosis
-н: James C. Barton, зэрэг
Хэвлэсэн: (2017-01-01)

Non-HFE hemochromatosis
-н: Paulo Caleb Júnior de Lima Santos, зэрэг
Хэвлэсэн: (2012-01-01)

Molecular basis of HFE-hemochromatosis
-н: Maja eVujic Spasic
Хэвлэсэн: (2014-03-01)

HIV-1 down-regulates the expression of CD1d via Nef.
-н: Chen, N, зэрэг
Хэвлэсэн: (2006)

Role of HFE in iron metabolism, hereditary haemochromatosis, anaemia of chronic disease, and secondary iron overload.
-н: Townsend, A, зэрэг
Хэвлэсэн: (2002)

Role of HFE in iron metabolism, hereditary haemochromatosis, anaemia of chronic disease, and secondary iron overload
-н: Townsend, A, зэрэг
Хэвлэсэн: (2002)

The structure and function of HFE.
-н: Drakesmith, H, зэрэг
Хэвлэсэн: (2000)

Analysis of HFE and non-HFE gene mutations in Brazilian patients with hemochromatosis
-н: Paulo Lisboa Bittencourt, зэрэг
Хэвлэсэн: (2009-01-01)

HFE hemochromatosis: an overview about therapeutic recommendations
-н: Rodolfo D. Cancado, зэрэг
Хэвлэсэн: (2022-01-01)

Inflammation can increase hepcidin in HFE‐hereditary hemochromatosis
-н: Wenke Moris, зэрэг
Хэвлэсэн: (2021-05-01)

Erratum: Role of HFE in iron metabolism, hereditary haemochomatosis, anaemia of chronic disease and secondary iron overload (Lancet (March 2) (786))
-н: Townsend, A, зэрэг
Хэвлэсэн: (2002)

Role of HFE in iron metabolism, hereditary haemochomatosis, anaemia of chronic disease, and secondary iron overload (vol 359, pg 786, 2002)
-н: Townsend, A, зэрэг
Хэвлэсэн: (2002)

Hemochromatosis gene (HFE) mutations in South East Asia: a potential for iron overload.
-н: Pointon, J, зэрэг
Хэвлэсэн: (2003)

Despite Genetic Iron Overload, Hfe‐Hemochromatosis Mice Do Not Show Bone Loss
-н: Alessa Wagner, зэрэг
Хэвлэсэн: (2019-09-01)

Homozygous deletion of HFE is the common cause of hemochromatosis in Sardinia
-н: Gérald Le Gac, зэрэг
Хэвлэсэн: (2010-04-01)

A time course of hepcidin response to iron challenge in patients with HFE and TFR2 hemochromatosis
-н: Domenico Girelli, зэрэг
Хэвлэсэн: (2011-04-01)

Utility of hepatic or total body iron burden in the assessment of advanced hepatic fibrosis in HFE hemochromatosis
-н: Justin Chin, зэрэг
Хэвлэсэн: (2019-12-01)

The effect of the hemochromatosis (HFE) genotype on lead load and iron metabolism among lead smelter workers.
-н: Guangqin Fan, зэрэг
Хэвлэсэн: (2014-01-01)

Iron as a Therapeutic Target in <i>HFE</i>-Related Hemochromatosis: Usual and Novel Aspects
-н: Olivier Loréal, зэрэг
Хэвлэсэн: (2018-11-01)

Hemochromatosis (HFE) gene mutations in Brazilian chronic hemodialysis patients
-н: F.V. Perícole, зэрэг
Хэвлэсэн: (2005-09-01)

Do pregnancies reduce iron overload in HFE hemochromatosis women? results from an observational prospective study
-н: Virginie Scotet, зэрэг
Хэвлэсэн: (2018-02-01)

Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y.
-н: James C Barton, зэрэг
Хэвлэсэн: (2022-01-01)

Iron overload phenotypes and HFE genotypes in white hemochromatosis and iron overload screening study participants without HFE p.C282Y/p.C282Y
-н: James C. Barton, зэрэг
Хэвлэсэн: (2022-01-01)

Investigating the dependency of HIV-1 replication in macrophages on cellular iron
-н: Drakesmith, H, зэрэг
Хэвлэсэн: (2007)

Effect of Native American ancestry on iron-related phenotypes of Alabama hemochromatosis probands with <it>HFE </it>C282Y homozygosity
-н: Barton Ellen H, зэрэг
Хэвлэсэн: (2006-03-01)

Studies at the hemochromatosis (HFE) locus : gene conversions, haplotypes, and association analysis
-н: Kamihara-Ting, Junne
Хэвлэсэн: (2008)

Chronic hepatitis B in children carried out of the hemochromatosis gene HFE
-н: F. I. Inoyatova, зэрэг
Хэвлэсэн: (2021-07-01)

Identification of novel non-HFE mutations in Chinese patients with hereditary hemochromatosis
-н: Wei Zhang, зэрэг
Хэвлэсэн: (2022-06-01)

Hereditary Hemochromatosis <it>(HFE) </it>genotypes in heart failure: Relation to etiology and prognosis
-н: Torp-Pedersen Christian, зэрэг
Хэвлэсэн: (2010-07-01)

HFE-Related Hemochromatosis in a Chinese Patient: The First Reported Case
-н: Wei Zhang, зэрэг
Хэвлэсэн: (2020-02-01)

Dietary Iron Overload and <i>Hfe<sup>−/−</sup></i> Related Hemochromatosis Alter Hepatic Mitochondrial Function
-н: Christine Fischer, зэрэг
Хэвлэсэн: (2021-11-01)

Hfe Gene Knock-Out in a Mouse Model of Hereditary Hemochromatosis Affects Bodily Iron Isotope Compositions
-н: Emmanuelle Albalat, зэрэг
Хэвлэсэн: (2021-10-01)

Clinical Manifestations of Hemochromatosis in HFE C282Y Homozygotes Identified by Screening
-н: Gordon D McLaren, зэрэг
Хэвлэсэн: (2008-01-01)

Association of HFE genotypes with hemochromatosis-related phenotypes in the All of Us research program
-н: Nandana D. Rao, зэрэг
Хэвлэсэн: (2025-01-01)

HFE Mutations in Caucasian Participants of the Hemochromatosis and Iron Overload Screening Study with Serum Ferritin Level <1000 μg/L
-н: Paul C Adams, зэрэг
Хэвлэсэн: (2013-01-01)

Identification of new ligands for the haemochromatosis protein HFE
-н: Drakesmith, H, зэрэг
Хэвлэсэн: (2007)

HLA-A*03, the hemochromatosis ancestral haplotype, and phenotypes of referred hemochromatosis probands with HFE p.C282Y homozygosity
-н: James C. Barton, зэрэг
Хэвлэсэн: (2022-06-01)