Nerve growth factor receptor mRNA distribution in human brain: normal levels in basal forebrain in Alzheimer's disease.

Nerve growth factor (NGF) receptor mRNA was found to be widely distributed throughout the human central nervous system, with the highest levels in the basal forebrain; this suggests that NGF may function as a retrograde trophic messenger for basal forebrain magnocellular cholinergic nerve cells. The...

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Bibliographic Details
Main Authors: Goedert, M, Fine, A, Dawbarn, D, Wilcock, G, Chao, M
Format: Journal article
Language:English
Published: 1989