An antigenic threshold for maintaining human immunodeficiency virus type 1-specific cytotoxic T lymphocytes.

BACKGROUND: Using the lymphocytic choriomeningitis virus (LCMV) model in mice, a number of studies show that memory cytotoxic T-lymphocyte (CTL) responses are maintained in the presence of continuous antigenic stimulation. Yet, other groups found that memory CTL specific for LCMV could last for a li...

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Bibliographic Details
Main Authors: Jin, X, Ogg, G, Bonhoeffer, S, Safrit, J, Vesanen, M, Bauer, D, Chen, D, Cao, Y, Demoitie, M, Zhang, L, Markowitz, M, Nixon, D, McMichael, A, Ho, D
Format: Journal article
Language:English
Published: 2000