Self-assembly and evolution of homomeric protein complexes.

We introduce a simple "patchy particle" model to study the thermodynamics and dynamics of self-assembly of homomeric protein complexes. Our calculations allow us to rationalize recent results for dihedral complexes. Namely, why evolution of such complexes naturally takes the system into a...

Description complète

Détails bibliographiques
Auteurs principaux: Villar, G, Wilber, A, Williamson, A, Thiara, P, Doye, J, Louis, A, Jochum, M, Lewis, A, Levy, E
Format: Journal article
Langue:English
Publié: American Physical Society 2009