NF-κB-inducing kinase is dispensable for activation of NF-κB in inflammatory settings but essential for lymphotoxin β receptor activation of NF-κB in primary human fibroblasts
The transcription factor NF-κB is of major importance in the biology of pro-inflammatory cytokines, such as TNF-α and IL-1α, and thereby is intimately involved in the process of inflammation. Understanding the mechanisms by which NF-κB is activated in response to inflammatory stimuli has become a ma...
| Main Authors: | , , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
2001
|