The small-nucleolar RNAs commonly used for microRNA normalisation correlate with tumour pathology and prognosis.
BACKGROUND: To investigate small-nucleolar RNAs (snoRNAs) as reference genes when measuring miRNA expression in tumour samples, given emerging evidence for their role in cancer. METHODS: Four snoRNAs, commonly used for normalisation, RNU44, RNU48, RNU43 and RNU6B, and miRNA known to be associated w...
Main Authors: | , , , , , , , , , , , , |
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Formato: | Journal article |
Idioma: | English |
Publicado: |
2011
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