The Jak/STAT pathway: a focus on pain in rheumatoid arthritis

Pain is a manifestation of rheumatoid arthritis (RA) that is mediated by inflammatory and non-inflammatory mechanisms and negatively affects quality of life. Recent findings from a Phase 3 clinical trial showed that patients with RA who were treated with a Janus kinase 1 (Jak1) and Janus kinase 2 (J...

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Bibliographic Details
Main Authors: Simon, LS, Taylor, PC, Choy, EH, Sebba, A, Quebe, A, Knopp, KL, Porreca, F
Format: Journal article
Language:English
Published: Elsevier 2020