Development of an open-source data analysis platform for high throughput screening in drug discovery and its application to E3 ligase IDOL inhibitor discovery project

<p>Alzheimer’s disease (AD) and cardiovascular diseases (CVDs) pose a major challenge in the coming decades considering an increasingly ageing population and demographic changes. MYLIP, also known as inducible degrader of the LDL receptor (IDOL) is an E3 ligase that is involved in the downregu...

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Bibliographic Details
Main Author: Christott, T
Other Authors: Christianson, J
Format: Thesis
Language:English
Published: 2024
Subjects: