Profound defects in pupillary responses to light in TRPM-channel null mice: a role for TRPM channels in non-image-forming photoreception.

TRPM1 is a spontaneously active non-selective cation channel that has recently been shown to play an important role in the depolarizing light responses of ON bipolar cells. Consistent with this role, mutations in the TRPM1 gene have been identified as a principal cause of congenital stationary night...

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Bibliographic Details
Main Authors: Hughes, S, Pothecary, C, Jagannath, A, Foster, R, Hankins, M, Peirson, S
Format: Journal article
Language:English
Published: 2012