Deep brain stimulation of the pedunculopontine region in the normal non-human primate.

Lesions in the pedunculopontine nucleus (PPN) cause akinesia. The PPN degenerates in Parkinson's disease. Stimulation of the PPN region induces stepping movements in rats and cats. These findings suggest that the PPN may play an important role in akines ia and that stimulating it may alleviate...

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Bibliographic Details
Main Authors: Nandi, D, Liu, X, Winter, J, Aziz, T, Stein, J
Format: Journal article
Language:English
Published: 2002