The frequency and amplitude of growth hormone secretory episodes as determined by deconvolution analysis are increased in adolescents with insulin dependent diabetes mellitus and are unaffected by short-term euglycaemia.

OBJECTIVE: High overnight plasma growth hormone (GH) levels in insulin-dependent diabetes mellitus (IDDM) are reflected in both an increase in the GH pulse amplitude and elevated baseline GH concentrations. To determine whether these are a result of an increase in GH secretory episodes, we undertook...

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Bibliographic Details
Main Authors: Pal, B, Matthews, D, Edge, J, Mullis, P, Hindmarsh, P, Dunger, D
Format: Journal article
Language:English
Published: 1993