The frequency and amplitude of growth hormone secretory episodes as determined by deconvolution analysis are increased in adolescents with insulin dependent diabetes mellitus and are unaffected by short-term euglycaemia.
OBJECTIVE: High overnight plasma growth hormone (GH) levels in insulin-dependent diabetes mellitus (IDDM) are reflected in both an increase in the GH pulse amplitude and elevated baseline GH concentrations. To determine whether these are a result of an increase in GH secretory episodes, we undertook...
المؤلفون الرئيسيون: | Pal, B, Matthews, D, Edge, J, Mullis, P, Hindmarsh, P, Dunger, D |
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التنسيق: | Journal article |
اللغة: | English |
منشور في: |
1993
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مواد مشابهة
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Half-life of exogenous growth hormone following suppression of endogenous growth hormone secretion with somatostatin in type I (insulin-dependent) diabetes mellitus.
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Evidence for a role for insulin and growth hormone in overnight regulation of 3-hydroxybutyrate in normal and diabetic adolescents.
حسب: Edge, J, وآخرون
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The application of deconvolution analysis to elucidate the pulsatile nature of growth hormone secretion using a variable half-life of growth hormone.
حسب: Hindmarsh, P, وآخرون
منشور في: (1990) -
Failure of current insulin regimes to meet the overnight requirements of adolescents with insulin-dependent diabetes.
حسب: Edge, J, وآخرون
منشور في: (1990)