Defining the genetic architecture of hypertrophic cardiomyopathy: re-evaluating the role of non-sarcomeric genes

AIM: Hypertrophic cardiomyopathy (HCM) exhibits genetic heterogeneity that is dominated by variation in eight sarcomeric genes. Genetic variation in a large number of non-sarcomeric genes has also been implicated in HCM but not formally assessed. Here we used very large case and control cohorts to d...

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Bibliographic Details
Main Authors: Walsh, R, Buchan, R, Wilk, A, John, S, Felkin, L, Thomson, K, Chiaw, T, Loong, C, Pua, C, Raphael, C, Prasad, S, Barton, P, Funke, B, Watkins, H, Ware, J, Cook, S
Format: Journal article
Language:English
Published: Oxford University Press 2017