A randomised pragmatic trial of corticosteroid optimization in severe asthma using a composite biomarker algorithm to adjust corticosteroid dose versus standard care: study protocol for a randomised trial

<p><strong>Background</strong><br/>Patients with difficult-to-control asthma consume 50–60% of healthcare costs attributed to asthma and cost approximately five-times more than patients with mild stable disease. Recent evidence demonstrates that not all patients with asthma h...

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Bibliographic Details
Main Authors: Hanratty, CE, Matthews, JG, Arron, JR, Choy, DF, Pavord, ID, Bradding, P, Brightling, CE, Chaudhuri, R, Cowan, DC, Djukanovic, R, Gallagher, N, Fowler, SJ, Hardman, TC, Harrison, T, Holweg, CT, Howarth, PH, Lordan, J, Mansur, AH, Menzies-Gow, A, Mosesova, S, Niven, RM, Robinson, DS, Shaw, DE, Walker, S, Woodcock, A, Heaney, LG, RASP-UK Consortium
Format: Journal article
Language:English
Published: BioMed Central 2018