Matrix metalloproteinase-1 and -9 promoter polymorphisms are not associated with an increased risk of uterine leiomyomas in a Japanese population.

OBJECTIVE: Matrix metalloproteinases (MMPs) play an important role in modeling and remodeling the extracellular matrix in leiomyomas. Hence, we investigated whether associations exist between leiomyomas and promoter polymorphisms in the MMP-1 and MMP-9 genes in a Japanese population. METHODS: We co...

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Bibliographic Details
Main Authors: Takemura, N, Yoshida, S, Kennedy, S, Deguchi, M, Ohara, N, Maruo, T
Format: Journal article
Language:English
Published: 2006