Matrix metalloproteinase-1 and -9 promoter polymorphisms are not associated with an increased risk of uterine leiomyomas in a Japanese population.
OBJECTIVE: Matrix metalloproteinases (MMPs) play an important role in modeling and remodeling the extracellular matrix in leiomyomas. Hence, we investigated whether associations exist between leiomyomas and promoter polymorphisms in the MMP-1 and MMP-9 genes in a Japanese population. METHODS: We co...
Main Authors: | Takemura, N, Yoshida, S, Kennedy, S, Deguchi, M, Ohara, N, Maruo, T |
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Format: | Journal article |
Language: | English |
Published: |
2006
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