Pyridine-N-oxide as a mild reoxidant which transforms osmium-catalyzed oxidative cyclization.

(Chemical Equation Presented) The PNOman can: The use of pyridine-N-oxide (PNO) transforms the catalytic oxidative cyclization to include the formation of pyrrolidines from N-Z-protected amino alcohols and amino acids (see scheme; Z = PhCH2OCO). This new method expands the scope of the oxidative cyc...

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Bibliographic Details
Main Authors: Donohoe, T, Wheelhouse, K, Lindsay-Scott, P, Glossop, P, Nash, I, Parker, J
Format: Journal article
Language:English
Published: 2008