Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

When selection is strong and beneficial alleles have a single origin, local reductions in genetic diversity are expected. However, when beneficial alleles have multiple origins or were segregating in the population prior to a change in selection regime, the impact on genetic diversity may be less cl...

詳細記述

書誌詳細
主要な著者: Nair, S, Nash, D, Sudimack, D, Jaidee, A, Barends, M, Uhlemann, A, Krishna, S, Nosten, F, Anderson, T
フォーマット: Journal article
言語:English
出版事項: 2007

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