Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

Recurrent gene amplification and soft selective sweeps during evolution of multidrug resistance in malaria parasites.

When selection is strong and beneficial alleles have a single origin, local reductions in genetic diversity are expected. However, when beneficial alleles have multiple origins or were segregating in the population prior to a change in selection regime, the impact on genetic diversity may be less cl...

Полное описание

Библиографические подробности
Главные авторы:	Nair, S, Nash, D, Sudimack, D, Jaidee, A, Barends, M, Uhlemann, A, Krishna, S, Nosten, F, Anderson, T
Формат:	Journal article
Язык:	English
Опубликовано:	2007

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