The role of distal regulatory elements in alpha globin transcription

The role of distal regulatory elements in alpha globin transcription

<p>Understanding the mechanisms of transcriptional control by cis-acting regulatory elements is one of the major goals in current molecular biology. Estimates of enhancer numbers in mammalian genomes extend to hundreds of thousands, outnumbering genes by an order of magnitude or more. Yet cu...

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Bibliografiske detaljer
Hovedforfatter:	Hay, D
Andre forfattere:	Higgs, D
Format:	Thesis
Sprog:	English
Udgivet:	2014
Fag:	Medical Sciences Molecular haematology

Lignende værker

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Investigating the specific roles of the growth factor kit ligand in the regulation of murine haematopoiesis
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Udgivet: (2015)

A study of regulatory T cells in allogeneic haematopoietic stem cell transplantation
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Udgivet: (2012)

Establishment and maintenance of the DNA methylation pattern in the human alpha-globin cluster
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Udgivet: (2013)

Dissecting human haematopoietic progenitors
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Udgivet: (2013)

Does Transcription of Remote alpha-Globin Regulatory Elements Affect Their Function?
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The study of DNA methylation anomalies in chronic lymphocytic leukaemia
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Inferring structural properties of protein-DNA binding using high-throughput sequencing. The paradigm of GATA1, KLF1 and their complexes GATA1/FOG1 and GATA1/KLF1. Insights into the transcriptional regulation of the erythroid cell lineage.
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Analysis of characteristics of randomized clinical trials in leukemia that are associated with how results are reported
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Udgivet: (2013)

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A descriptive study of randomised trials of treatments for childhood acute lymphoblastic leukaemia
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Elucidating the input of notch ligand delta-like 4 (dll4) in zebrafish blood stem cell ontogeny
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Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients
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Udgivet: (2009)

High sensitivity C-reactive protein and glycated hemoglobin levels as dominant predictors of all-cause dementia: a nationwide population-based cohort study
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Decoding human bone marrow hematopoietic stem and progenitor cells from fetal to birth
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Udgivet: (2024-08-01)

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Udgivet: (2014)

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Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice.
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Udgivet: (1992)

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Haematological evaluation of medically treated cases of pyometra in dogs
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Udgivet: (2020-01-01)

Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5
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Udgivet: (2010)

A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element.
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Udgivet: (2006)

Study of platelet-mediated clumping adhesion phenotypes in Plasmodium falciparum malaria
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Udgivet: (2015)

Provincial heterogeneity in the management of care cascade for hypertension, diabetes, and dyslipidaemia in China: Analysis of nationally representative population-based survey
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Udgivet: (2022)

Ratio of monocytes to lymphocytes in peripheral blood identiﬁes adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy
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Udgivet: (2013)

Should a clinical rotation in hematology be mandatory for undergraduate medical students?
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Udgivet: (2016-09-01)

Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart.
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Udgivet: (1983)

Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.
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Udgivet: (2002)

Expression of the human alpha-globin cluster in the absence of the major regulatory element Mcs-R2
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Udgivet: (2018)

Deletion of the mouse alpha globin regulatory element (HS-26) has an unexpectedly mild phenotype.
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Udgivet: (2003)

A Rare Translocation in a Paediatric Myelodysplastic Syndrome
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Udgivet: (2018-12-01)

Combined Effect of Inflammation and Hyperglycemia on Mild Cognitive Impairment and Associated Dietary Patterns in an Older Taiwanese Population
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Udgivet: (2022)

Collaboration of Ezh2 and Runx1 inactivating mutations in malignant haematopoiesis
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Udgivet: (2017)