The role of distal regulatory elements in alpha globin transcription

The role of distal regulatory elements in alpha globin transcription

<p>Understanding the mechanisms of transcriptional control by cis-acting regulatory elements is one of the major goals in current molecular biology. Estimates of enhancer numbers in mammalian genomes extend to hundreds of thousands, outnumbering genes by an order of magnitude or more. Yet cu...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолч:	Hay, D
Бусад зохиолчид:	Higgs, D
Формат:	Дипломын ажил
Хэл сонгох:	English
Хэвлэсэн:	2014
Нөхцлүүд:	Medical Sciences Molecular haematology

Ижил төстэй зүйлс

Locus-wide studies into the transcriptional regulation of Runx1 in developmental hematopoiesis
-н: Jarratt, A
Хэвлэсэн: (2012)

Investigating the specific roles of the growth factor kit ligand in the regulation of murine haematopoiesis
-н: Facchini, RM
Хэвлэсэн: (2015)

A study of regulatory T cells in allogeneic haematopoietic stem cell transplantation
-н: Danby, RD
Хэвлэсэн: (2012)

Establishment and maintenance of the DNA methylation pattern in the human alpha-globin cluster
-н: Gaentzsch, R
Хэвлэсэн: (2013)

Dissecting human haematopoietic progenitors
-н: Samitsch, M
Хэвлэсэн: (2013)

Does Transcription of Remote alpha-Globin Regulatory Elements Affect Their Function?
-н: Kowalczyk, MS, зэрэг
Хэвлэсэн: (2009)

The emergence and early fate decisions of stem and progenitor cells in the haematopoietic system
-н: Lutteropp, M
Хэвлэсэн: (2012)

The mouse alpha-globin locus regulatory element.
-н: Gourdon, G, зэрэг
Хэвлэсэн: (1995)

The study of DNA methylation anomalies in chronic lymphocytic leukaemia
-н: Roy, NBA
Хэвлэсэн: (2011)

Inferring structural properties of protein-DNA binding using high-throughput sequencing. The paradigm of GATA1, KLF1 and their complexes GATA1/FOG1 and GATA1/KLF1. Insights into the transcriptional regulation of the erythroid cell lineage.
-н: Oikonomopoulos, S
Хэвлэсэн: (2014)

Analysis of characteristics of randomized clinical trials in leukemia that are associated with how results are reported
-н: Burrett, J, зэрэг
Хэвлэсэн: (2011)

Characterising the cell biology of leukemic stem cells in acute myeloid leukemia.
-н: Cornforth, TV
Хэвлэсэн: (2013)

Lim-only domain proteins in developmental haematopoiesis
-н: Tuladhar, K
Хэвлэсэн: (2012)

Autophagy in hematopoiesis and acute myeloid leukemia
-н: Watson, A
Хэвлэсэн: (2014)

A descriptive study of randomised trials of treatments for childhood acute lymphoblastic leukaemia
-н: Burrett, J, зэрэг
Хэвлэсэн: (2002)

Elucidating the input of notch ligand delta-like 4 (dll4) in zebrafish blood stem cell ontogeny
-н: Schneider, J, зэрэг
Хэвлэсэн: (2014)

Role of the haematopoietic transcription factor SCL in mesoderm development
-н: Green, A
Хэвлэсэн: (2012)

Genetic variation on chromosome 6 influences F cell levels in healthy individuals of African descent and HbF levels in sickle cell patients
-н: Creary, L, зэрэг
Хэвлэсэн: (2009)

High sensitivity C-reactive protein and glycated hemoglobin levels as dominant predictors of all-cause dementia: a nationwide population-based cohort study
-н: Fan, Yen-Chun, зэрэг
Хэвлэсэн: (2022)

Decoding human bone marrow hematopoietic stem and progenitor cells from fetal to birth
-н: Xiaowei Xie, зэрэг
Хэвлэсэн: (2024-08-01)

Focal adhesion-mediated directional cell migration guided by gradient-stretched substrate
-н: Zijia Chen, зэрэг
Хэвлэсэн: (2024-08-01)

Loss of chaperone protein in human cancer
-н: Adighibe, O
Хэвлэсэн: (2012)

Risk factors for haemorrhage in patients with haematological malignancies
-н: Estcourt, LJ
Хэвлэсэн: (2014)

Regulating stem cell fate within microenvironmental niches
-н: Buglass, SK
Хэвлэсэн: (2014)

Analysis of the human alpha globin upstream regulatory element (HS-40) in transgenic mice.
-н: Sharpe, J, зэрэг
Хэвлэсэн: (1992)

Transcriptional promiscuity of the human alpha-globin gene.
-н: Whitelaw, E, зэрэг
Хэвлэсэн: (1989)

Haematological evaluation of medically treated cases of pyometra in dogs
-н: M.P. Unnikrishnan, зэрэг
Хэвлэсэн: (2020-01-01)

Forward genetic and cellular studies of immune regulation: the roles of Carma1, Interleukin-10 and Gimap5
-н: Barnes, MJ
Хэвлэсэн: (2010)

A novel deletion causing alpha thalassemia clarifies the importance of the major human alpha globin regulatory element.
-н: Viprakasit, V, зэрэг
Хэвлэсэн: (2006)

Study of platelet-mediated clumping adhesion phenotypes in Plasmodium falciparum malaria
-н: Onyambu, F, зэрэг
Хэвлэсэн: (2015)

Provincial heterogeneity in the management of care cascade for hypertension, diabetes, and dyslipidaemia in China: Analysis of nationally representative population-based survey
-н: Zhao, Yang, зэрэг
Хэвлэсэн: (2022)

Ratio of monocytes to lymphocytes in peripheral blood identiﬁes adults at risk of incident tuberculosis among HIV-infected adults initiating antiretroviral therapy
-н: Naranbhai, V, зэрэг
Хэвлэсэн: (2013)

Should a clinical rotation in hematology be mandatory for undergraduate medical students?
-н: Mandan J, зэрэг
Хэвлэсэн: (2016-09-01)

Transcriptional activity of the human pseudogene psi alpha globin compared with alpha globin, its functional gene counterpart.
-н: Whitelaw, E, зэрэг
Хэвлэсэн: (1983)

Deletion of the mouse alpha-globin regulatory element (HS -26) has an unexpectedly mild phenotype.
-н: Anguita, E, зэрэг
Хэвлэсэн: (2002)

Expression of the human alpha-globin cluster in the absence of the major regulatory element Mcs-R2
-н: Badat, M, зэрэг
Хэвлэсэн: (2018)

Deletion of the mouse alpha globin regulatory element (HS-26) has an unexpectedly mild phenotype.
-н: Anguita, E, зэрэг
Хэвлэсэн: (2003)

A Rare Translocation in a Paediatric Myelodysplastic Syndrome
-н: Rachana Kiran Koppalkar, зэрэг
Хэвлэсэн: (2018-12-01)

Combined Effect of Inflammation and Hyperglycemia on Mild Cognitive Impairment and Associated Dietary Patterns in an Older Taiwanese Population
-н: Fan, Yen-Chun, зэрэг
Хэвлэсэн: (2022)

Collaboration of Ezh2 and Runx1 inactivating mutations in malignant haematopoiesis
-н: Booth, C
Хэвлэсэн: (2017)