Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.

We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Lennerstrand, J, Stammers, D, Larder, B
التنسيق: Journal article
اللغة:English
منشور في: 2001