Biochemical mechanism of human immunodeficiency virus type 1 reverse transcriptase resistance to stavudine.
We have found a close correlation between viral stavudine (d4T) resistance and resistance to d4T-triphosphate at the human immunodeficiency virus type 1 reverse transcriptase (RT) level. RT from site-directed mutants with 69S-XX codon insertions and/or conventional zidovudine resistance mutations se...
Հիմնական հեղինակներ: | Lennerstrand, J, Stammers, D, Larder, B |
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Ձևաչափ: | Journal article |
Լեզու: | English |
Հրապարակվել է: |
2001
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Նմանատիպ նյութեր
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Correlation between viral resistance to zidovudine and resistance at the reverse transcriptase level for a panel of human immunodeficiency virus type 1 mutants.
: Lennerstrand, J, և այլն
Հրապարակվել է: (2001) -
Crystal structures of Zidovudine- or Lamivudine-resistant human immunodeficiency virus type 1 reverse transcriptases containing mutations at codons 41, 184, and 215.
: Chamberlain, P, և այլն
Հրապարակվել է: (2002) -
A mutation in the 3' region of the human immunodeficiency virus type 1 reverse transcriptase (Y318F) associated with nonnucleoside reverse transcriptase inhibitor resistance.
: Harrigan, P, և այլն
Հրապարակվել է: (2002) -
STRUCTURAL STUDIES ON HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE
: Stammers, D, և այլն
Հրապարակվել է: (1990) -
THE GROWTH AND CHARACTERIZATION OF CRYSTALS OF HUMAN-IMMUNODEFICIENCY-VIRUS (HIV) REVERSE-TRANSCRIPTASE
: Jones, E, և այլն
Հրապարակվել է: (1993)