p53-specific CD8+ T-cell responses in individuals with cutaneous squamous cell carcinoma.

BACKGROUND: Systemic immunosuppression is a significant risk factor for cutaneous squamous cell carcinoma (SCC). p53 is mutated and overexpressed in up to 90% of cutaneous SCC lesions. Despite considerable evidence that the immune response is important in the control of cutaneous SCC, there are no s...

Full description

Bibliographic Details
Main Authors: Black, A, Bailey, A, Jones, L, Turner, R, Hollowood, K, Ogg, G
Format: Journal article
Language:English
Published: 2005