p53-specific CD8+ T-cell responses in individuals with cutaneous squamous cell carcinoma.
BACKGROUND: Systemic immunosuppression is a significant risk factor for cutaneous squamous cell carcinoma (SCC). p53 is mutated and overexpressed in up to 90% of cutaneous SCC lesions. Despite considerable evidence that the immune response is important in the control of cutaneous SCC, there are no s...
Main Authors: | Black, A, Bailey, A, Jones, L, Turner, R, Hollowood, K, Ogg, G |
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Format: | Journal article |
Language: | English |
Published: |
2005
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