Use of methods for specifying the target difference in randomised controlled trial sample size calculations: Two surveys of trialists' practice.
BACKGROUND: Central to the design of a randomised controlled trial (RCT) is a calculation of the number of participants needed. This is typically achieved by specifying a target difference, which enables the trial to identify a difference of a particular magnitude should one exist. Seven methods hav...
Main Authors: | Cook, J, Hislop, J, Altman, D, Briggs, A, Fayers, P, Norrie, J, Ramsay, C, Harvey, I, Vale, L |
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格式: | Journal article |
语言: | English |
出版: |
SAGE Publications
2014
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