DNA copy-number alterations underlie gene expression differences between microsatellite stable and unstable colorectal cancers.

PURPOSE: About 15% of colorectal cancers harbor microsatellite instability (MSI). MSI-associated gene expression changes have been identified in colorectal cancers, but little overlap exists between signatures hindering an assessment of overall consistency. Little is known about the causes and down...

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Príomhchruthaitheoirí: Jorissen, R, Lipton, L, Gibbs, P, Chapman, M, Desai, J, Jones, I, Yeatman, T, East, P, Tomlinson, I, Verspaget, H, Aaltonen, L, Kruhøffer, M, Orntoft, T, Andersen, C, Sieber, O
Formáid: Journal article
Teanga:English
Foilsithe / Cruthaithe: 2008