Cellular and microenvironmental cues that promote macrophage fusion and foreign body response

During the foreign body response (FBR), macrophages fuse to form foreign body giant cells (FBGCs). Modulation of FBGC formation can prevent biomaterial degradation and loss of therapeutic efficacy. However, the microenvironmental cues that dictate FBGC formation are poorly understood with conflictin...

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Bibliografski detalji
Glavni autori: Stewart, CL, Hook, AL, Zelzer, M, Marlow, M, Piccinini, AM
Format: Journal article
Jezik:English
Izdano: Frontiers Media 2024