Histone recognition and large-scale structural analysis of the human bromodomain family.
Bromodomains (BRDs) are protein interaction modules that specifically recognize ε-N-lysine acetylation motifs, a key event in the reading process of epigenetic marks. The 61 BRDs in the human genome cluster into eight families based on structure/sequence similarity. Here, we present 29 high-resoluti...
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
2012
|