A convenient catalytic asymmetric conjugate addition reaction to enones using alkylzirconium reagents

Alkylzirconium reagents undergo highly enantioselective copper-catalysed 1,4-addition reaction to cyclic enones. These reactions use alkylmetal species generated in situ from alkenes and the Schwartz reagent, and do not require premade organometallic reagents. The reactions have been performed on pr...

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Bibliographic Details
Main Authors: Maksymowicz, R, Sidera, M, Roth, P, Fletcher, S
Format: Journal article
Language:English
Published: 2013