Transient cross-reactive immune responses can orchestrate antigenic variation in malaria.

The malaria parasite Plasmodium falciparum has evolved to prolong its duration of infection by antigenic variation of a major immune target on the surface of the infected red blood cell. This immune evasion strategy depends on the sequential, rather than simultaneous, appearance of immunologically d...

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Bibliographic Details
Main Authors: Recker, M, Nee, S, Bull, P, Kinyanjui, S, Marsh, K, Newbold, C, Gupta, S
Format: Journal article
Language:English
Published: 2004