Spirocyclic systems derived from pyroglutamic acid.
The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated.
Main Authors: | , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2011
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Summary: | The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated. |
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