Spirocyclic systems derived from pyroglutamic acid.
The synthesis and likely conformational structure of rigid spirocyclic bislactams and lactam-lactones derived from pyroglutamic acid, and their suitability as lead structures for applications in drug development programmes using cheminformatic analysis, has been investgated.
Hlavní autoři: | Cowley, A, Hill, T, Kocis, P, Moloney, M, Stevenson, R, Thompson, A |
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Médium: | Journal article |
Jazyk: | English |
Vydáno: |
2011
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