Lipid-dependent regulation of ion channels and g protein-coupled receptors: insights from structures and simulations
Ion channels and G protein-coupled receptors (GPCRs) are regulated by lipids in their membrane environment. Structural studies combined with biophysical and molecular simulation investigations reveal interaction sites for specific lipids on membrane protein structures. For K channels, PIP2 plays a k...
Autori principali: | Duncan, AL, Song, W, Sansom, MSP |
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Natura: | Journal article |
Lingua: | English |
Pubblicazione: |
Annual Reviews
2020
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