Crystal structure of signal regulatory protein gamma (SIRPγ) in complex with an antibody Fab fragment

<p><strong>Background</strong>: Signal Regulatory Protein γ (SIRPγ) is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. SIRPγ is expressed on T lymphocytes where it appears to be involved in the integrin-in...

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Bibliographic Details
Main Authors: Nettleship, J, Ren, J, Scott, D, Rahman, N, Hatherley, D, Zhao, Y, Stuart, D, Barclay, N, Owens, R
Format: Journal article
Language:English
Published: BioMed Central 2013