History of tuberculosis disease is associated with genetic regulatory variation in Peruvians

A quarter of humanity is estimated to have been exposed to Mycobacterium tuberculosis (Mtb) with a 5–10% risk of developing tuberculosis (TB) disease. Variability in responses to Mtb infection could be due to host or pathogen heterogeneity. Here, we focused on host genetic variation in a Peruvian po...

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Bibliographic Details
Main Authors: Nieto-Caballero, VE, Reijneveld, JF, Ruvalcaba, A, Innocenzi, G, Abeydeera, N, Asgari, S, Lopez, K, Iwany, SK, Luo, Y, Nathan, A, Fernandez-Salinas, D, Chiñas, M, Huang, C, Zhang, Z, León, SR, Calderon, RI, Lecca, L, Budzik, JM, Murray, M, Van Rhijn, I, Raychaudhuri, S, Moody, DB, Suliman, S, Gutierrez-Arcelus, M
Format: Journal article
Language:English
Published: Public Library of Science 2024