Estimation of maximal affinities between T-cell receptors and MHC/peptide complexes.
Recognition of peptide/MHC complexes by T-cell receptors (TCRs) is a critical step for T-cell activation. We studied T-cell activation as a function of this interaction using a mathematical model. Unlike other models analysing TCR-MHC/peptide interactions, this study takes into account that both TCR...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1998
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