Estimation of maximal affinities between T-cell receptors and MHC/peptide complexes.

Recognition of peptide/MHC complexes by T-cell receptors (TCRs) is a critical step for T-cell activation. We studied T-cell activation as a function of this interaction using a mathematical model. Unlike other models analysing TCR-MHC/peptide interactions, this study takes into account that both TCR...

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Détails bibliographiques
Auteurs principaux: Salzmann, M, Bachmann, M
Format: Journal article
Langue:English
Publié: 1998