Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Ongoing treatments for genetic developmental disorders of the central nervous system are mostly symptomatic and do not correct the genetic cause. Recent identification of common mechanisms between diseases has suggested that new therapeutic targets could be applied across intellectual disabilities w...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron:	Faundez, V, De Toma, I, Bardoni, B, Bartesaghi, R, Nizetic, D, de la Torre, R, Kadosh, R, Herault, Y, Dierssen, M, Potier, M-C
Fformat:	Journal article
Iaith:	English
Cyhoeddwyd:	Elsevier 2018

Eitemau Tebyg

Modeling Fragile X Syndrome in Drosophila
gan: Małgorzata Drozd, et al.
Cyhoeddwyd: (2018-04-01)

Fragile X Syndrome as an interneuronopathy: a lesson for future studies and treatments
gan: Alessandra Tempio, et al.
Cyhoeddwyd: (2023-04-01)

Fragile X Mental Retardation Protein: To Be or Not to Be a Translational Enhancer
gan: Thomas Maurin, et al.
Cyhoeddwyd: (2018-12-01)

A Male with Cooccurrence of Down Syndrome and Fragile X Syndrome
gan: Tovi Anderson, et al.
Cyhoeddwyd: (2013-01-01)

The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?
gan: Sara Castagnola, et al.
Cyhoeddwyd: (2017-11-01)

Síndrome frágil X Fragile X syndrome
gan: Miguel Lugones Botell, et al.
Cyhoeddwyd: (2006-09-01)

The fragile X syndrome.
gan: Flannery, A, et al.
Cyhoeddwyd: (1995)

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions
gan: Snow Bach, et al.
Cyhoeddwyd: (2021-11-01)

CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
gan: Barbara eBardoni, et al.
Cyhoeddwyd: (2014-03-01)

The fragile X syndrome.
gan: Hirst, M, et al.
Cyhoeddwyd: (1992)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
gan: Siew, Wei Hong, et al.
Cyhoeddwyd: (2013)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
gan: Wei-Hong eSiew, et al.
Cyhoeddwyd: (2013-04-01)

Síndrome frágil X Fragile X Syndrome
Cyhoeddwyd: (2007-03-01)

Learning Potential is Useful in Pre-schoolers with Fragile X and Down Syndrome
gan: Mª Auxiliadora Robles-Bello, et al.
Cyhoeddwyd: (2018-04-01)

Molecular studies of the fragile X syndrome.
gan: Knight, S, et al.
Cyhoeddwyd: (1992)

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19
gan: Ilario De Toma, et al.
Cyhoeddwyd: (2021-01-01)

The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome
gan: Emily Lorang, et al.
Cyhoeddwyd: (2017-12-01)

Drugs development and fragile X syndrome translational success story
gan: Budimirović Dejan, et al.
Cyhoeddwyd: (2016-01-01)

Fragile X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (1987-11-01)

Fragile-X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (1988-03-01)

Prenatal diagnosis of fragile X syndrome.
gan: Hirst, M, et al.
Cyhoeddwyd: (1991)

Social Factors Influence Behavior in the Novel Object Recognition Task in a Mouse Model of Down Syndrome
gan: Cesar Sierra, et al.
Cyhoeddwyd: (2021-11-01)

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome
gan: Jonathan W. Lovelace, et al.
Cyhoeddwyd: (2018-07-01)

Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome
gan: Sang S. Seo, et al.
Cyhoeddwyd: (2022-06-01)

Psychopathology in Fragile X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (1989-02-01)

Fragile X Syndrome Recognition
gan: J Gordon Millichap
Cyhoeddwyd: (1989-02-01)

Neuroanatomy of Fragile X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (1991-02-01)

Diagnosis of Fragile X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (1991-12-01)

Epilepsy and Fragile X Syndrome
gan: J Gordon Millichap
Cyhoeddwyd: (2003-01-01)

Fragile X Syndrome Workshop
gan: J Gordon Millichap
Cyhoeddwyd: (2000-10-01)

Astrocytes in fragile X syndrome
gan: Karo Talvio, et al.
Cyhoeddwyd: (2024-01-01)

Screening for fragile X syndrome.
gan: Murray, et al.
Cyhoeddwyd: (1997-01-01)

Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome
gan: Anne Hoffmann, et al.
Cyhoeddwyd: (2022-04-01)

Specificity: A Phenotypic Comparison of Communication-Relevant Domains Between Youth With Down Syndrome and Fragile X Syndrome
gan: Laura del Hoyo Soriano, et al.
Cyhoeddwyd: (2018-10-01)

Molecular analysis of the fragile X syndrome.
gan: Knight, S, et al.
Cyhoeddwyd: (1992)

Pathological Plasticity in Fragile X Syndrome
gan: Brandon S. Martin, et al.
Cyhoeddwyd: (2012-01-01)

Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome
gan: Tomer Illouz, et al.
Cyhoeddwyd: (2021-06-01)

Origins of the fragile X syndrome mutation.
gan: Hirst, M, et al.
Cyhoeddwyd: (1993)

Genotype prediction in the fragile X syndrome.
gan: Hirst, M, et al.
Cyhoeddwyd: (1991)

Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
gan: Rochelle L. Coulson, et al.
Cyhoeddwyd: (2024-04-01)