Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Translating molecular advances in Down syndrome and Fragile X syndrome into therapies

Ongoing treatments for genetic developmental disorders of the central nervous system are mostly symptomatic and do not correct the genetic cause. Recent identification of common mechanisms between diseases has suggested that new therapeutic targets could be applied across intellectual disabilities w...

Deskribapen osoa

Xehetasun bibliografikoak
Egile Nagusiak:	Faundez, V, De Toma, I, Bardoni, B, Bartesaghi, R, Nizetic, D, de la Torre, R, Kadosh, R, Herault, Y, Dierssen, M, Potier, M-C
Formatua:	Journal article
Hizkuntza:	English
Argitaratua:	Elsevier 2018

Antzeko izenburuak

Modeling Fragile X Syndrome in Drosophila
nork: Małgorzata Drozd, et al.
Argitaratua: (2018-04-01)

Fragile X Syndrome as an interneuronopathy: a lesson for future studies and treatments
nork: Alessandra Tempio, et al.
Argitaratua: (2023-04-01)

Fragile X Mental Retardation Protein: To Be or Not to Be a Translational Enhancer
nork: Thomas Maurin, et al.
Argitaratua: (2018-12-01)

A Male with Cooccurrence of Down Syndrome and Fragile X Syndrome
nork: Tovi Anderson, et al.
Argitaratua: (2013-01-01)

The Search for an Effective Therapy to Treat Fragile X Syndrome: Dream or Reality?
nork: Sara Castagnola, et al.
Argitaratua: (2017-11-01)

Síndrome frágil X Fragile X syndrome
nork: Miguel Lugones Botell, et al.
Argitaratua: (2006-09-01)

The fragile X syndrome.
nork: Flannery, A, et al.
Argitaratua: (1995)

Rett Syndrome and Fragile X Syndrome: Different Etiology With Common Molecular Dysfunctions
nork: Snow Bach, et al.
Argitaratua: (2021-11-01)

CYFIP family proteins between autism and intellectual disability: links with Fragile X syndrome
nork: Barbara eBardoni, et al.
Argitaratua: (2014-03-01)

The fragile X syndrome.
nork: Hirst, M, et al.
Argitaratua: (1992)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
nork: Siew, Wei Hong, et al.
Argitaratua: (2013)

MicroRNAs and intellectual disability (ID) in Down syndrome, X-linked ID and Fragile X syndrome
nork: Wei-Hong eSiew, et al.
Argitaratua: (2013-04-01)

Síndrome frágil X Fragile X Syndrome
Argitaratua: (2007-03-01)

Learning Potential is Useful in Pre-schoolers with Fragile X and Down Syndrome
nork: Mª Auxiliadora Robles-Bello, et al.
Argitaratua: (2018-04-01)

Molecular studies of the fragile X syndrome.
nork: Knight, S, et al.
Argitaratua: (1992)

Network analysis of Down syndrome and SARS-CoV-2 identifies risk and protective factors for COVID-19
nork: Ilario De Toma, et al.
Argitaratua: (2021-01-01)

The impact of autism spectrum disorder symptoms on gesture use in fragile X syndrome and Down syndrome
nork: Emily Lorang, et al.
Argitaratua: (2017-12-01)

Drugs development and fragile X syndrome translational success story
nork: Budimirović Dejan, et al.
Argitaratua: (2016-01-01)

Fragile X Syndrome
nork: J Gordon Millichap
Argitaratua: (1987-11-01)

Fragile-X Syndrome
nork: J Gordon Millichap
Argitaratua: (1988-03-01)

Prenatal diagnosis of fragile X syndrome.
nork: Hirst, M, et al.
Argitaratua: (1991)

Social Factors Influence Behavior in the Novel Object Recognition Task in a Mouse Model of Down Syndrome
nork: Cesar Sierra, et al.
Argitaratua: (2021-11-01)

Translation-relevant EEG phenotypes in a mouse model of Fragile X Syndrome
nork: Jonathan W. Lovelace, et al.
Argitaratua: (2018-07-01)

Excess ribosomal protein production unbalances translation in a model of Fragile X Syndrome
nork: Sang S. Seo, et al.
Argitaratua: (2022-06-01)

Psychopathology in Fragile X Syndrome
nork: J Gordon Millichap
Argitaratua: (1989-02-01)

Fragile X Syndrome Recognition
nork: J Gordon Millichap
Argitaratua: (1989-02-01)

Neuroanatomy of Fragile X Syndrome
nork: J Gordon Millichap
Argitaratua: (1991-02-01)

Diagnosis of Fragile X Syndrome
nork: J Gordon Millichap
Argitaratua: (1991-12-01)

Epilepsy and Fragile X Syndrome
nork: J Gordon Millichap
Argitaratua: (2003-01-01)

Fragile X Syndrome Workshop
nork: J Gordon Millichap
Argitaratua: (2000-10-01)

Astrocytes in fragile X syndrome
nork: Karo Talvio, et al.
Argitaratua: (2024-01-01)

Screening for fragile X syndrome.
nork: Murray, et al.
Argitaratua: (1997-01-01)

Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome
nork: Anne Hoffmann, et al.
Argitaratua: (2022-04-01)

Specificity: A Phenotypic Comparison of Communication-Relevant Domains Between Youth With Down Syndrome and Fragile X Syndrome
nork: Laura del Hoyo Soriano, et al.
Argitaratua: (2018-10-01)

Molecular analysis of the fragile X syndrome.
nork: Knight, S, et al.
Argitaratua: (1992)

Pathological Plasticity in Fragile X Syndrome
nork: Brandon S. Martin, et al.
Argitaratua: (2012-01-01)

Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome
nork: Tomer Illouz, et al.
Argitaratua: (2021-06-01)

Origins of the fragile X syndrome mutation.
nork: Hirst, M, et al.
Argitaratua: (1993)

Genotype prediction in the fragile X syndrome.
nork: Hirst, M, et al.
Argitaratua: (1991)

Translational modulator ISRIB alleviates synaptic and behavioral phenotypes in Fragile X syndrome
nork: Rochelle L. Coulson, et al.
Argitaratua: (2024-04-01)