Haplotype homozygosity and derived alleles in the human genome

Haplotype-based techniques are being used to estimate the relative age of alleles—particularly in screening loci for signals of recent positive selection—but does this approach capture even coarse age differences? Using simulations and empirical data from the International HapMap Project, we show th...

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Bibliographic Details
Main Authors: Fry, A, Trafford, C, Kimber, M, Rockett, K, Kwiatkowski, D
Other Authors: The American Society of Human Genetics
Format: Journal article
Language:English
Published: University of Chicago Press 2006
Subjects: