Mepolizumab for severe eosinophilic asthma (DREAM): a multicentre, double-blind, placebo-controlled trial.

BACKGROUND: Some patients with severe asthma have recurrent asthma exacerbations associated with eosinophilic airway inflammation. Early studies suggest that inhibition of eosinophilic airway inflammation with mepolizumab-a monoclonal antibody against interleukin 5-is associated with a reduced risk...

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Main Authors: Pavord, I, Korn, S, Howarth, P, Bleecker, E, Buhl, R, Keene, O, Ortega, H, Chanez, P
格式: Journal article
语言:English
出版: 2012