Mechanisms of cardiac iron homeostasis and their importance to heart function

Heart disease is a common manifestation in conditions of iron imbalance. Normal heart function requires coupling of iron supply for oxidative phosphorylation and redox signalling with tight control of intracellular iron to below levels at which excessive ROS are generated. Iron supply to the heart i...

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Autore principale: Lakhal-Littleton, S
Natura: Journal article
Lingua:English
Pubblicazione: Elsevier 2018