New methods for the synthesis of naphthyl amines; application to the synthesis of dihydrosanguinarine, sanguinarine, oxysanguinarine and (±)-maclekarpines B and C.

A new method for preparing naphthyl amines from 1,5 unsaturated dicarbonyl precursors is described; the utility of this new method was proven in the syntheses of several natural products, all containing the benzo[c]phenanthridine core and enabled by a radical promoted cyclisation of the naphthyl ami...

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Bibliographic Details
Main Authors: Tatton, MR, Simpson, I, Donohoe, T
Format: Journal article
Language:English
Published: Royal Society of Chemistry 2014