Effects of catechol-o-methyltransferase on reinforcement learning and mesolimbic dopamine transmission

<p>The enzyme catechol-O-methyltransferase (COMT) plays an important role in the breakdown of dopamine in prefrontal cortex (PFC), but relatively little is known about its effects on nucleus accumbens (NAc) dopamine function. In this study, a transgenic mouse model of the Val158Met polymorphis...

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Bibliographic Details
Main Author: Huber, A
Other Authors: Walton, M
Format: Thesis
Language:English
Published: 2015
Subjects: