Effects of catechol-o-methyltransferase on reinforcement learning and mesolimbic dopamine transmission

Effects of catechol-o-methyltransferase on reinforcement learning and mesolimbic dopamine transmission

<p>The enzyme catechol-O-methyltransferase (COMT) plays an important role in the breakdown of dopamine in prefrontal cortex (PFC), but relatively little is known about its effects on nucleus accumbens (NAc) dopamine function. In this study, a transgenic mouse model of the Val158Met polymorphis...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखक:	Huber, A
अन्य लेखक:	Walton, M
स्वरूप:	थीसिस
भाषा:	English
प्रकाशित:	2015
विषय:	Neurosciences

समान संसाधन

Separate and interactive effects of catechol-o-methyltransferase and tetrahydrocannabinol on frontostriatal dopamine function
द्वारा: Stumpenhorst, K
प्रकाशित: (2017)

The magnetoencephalographic signature of catechol-O-methyltransferase
द्वारा: Farrell, SM
प्रकाशित: (2013)

Mesolimbic dopamine and circuit level mechanisms in action initiation and restraint
द्वारा: Jenkins, G
प्रकाशित: (2023)

The role of catechol-O-methyltransferase (COMT) in hippocampal function
द्वारा: Laatikainen, L
प्रकाशित: (2010)

Catechol-o-methyltransferase (COMT) influences dopamine metabolism outside of the prefrontal cortex
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2011)

The role of catechol-O-methyltransferase in reward processing and addiction.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2012)

Sexually dimorphic effects of catechol-O-methyltransferase (COMT) inhibition on dopamine metabolism in multiple brain regions
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2013)

Modulation of hippocampal dopamine metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition.
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2012)

The catechol-O-methyltransferase gene: its regulation and polymorphisms.
द्वारा: Tunbridge, E
प्रकाशित: (2010)

The role of catechol-O-methyltransferase in processing affective stimuli
द्वारा: Dalton, N
प्रकाशित: (2016)

Dissociative catecholaminergic modulation of visual attention: Differential effects of Catechol-O-methyltransferase and dopamine beta-hydroxylase genes on visual attention
द्वारा: Shalev, N, और अन्य
प्रकाशित: (2019)

Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2004)

Catechol-O-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2004)

Catechol-o-methyltransferase, cognition, and psychosis: Val158Met and beyond.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2006)

Catechol-O-methyltransferase activity does not influence emotional processing in men
द्वारा: Martens, MA, और अन्य
प्रकाशित: (2022)

Catechol-O-methyltransferase (COMT) influences the connectivity of the prefrontal cortex at rest.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2013)

metabolism and hippocampal-dependent cognitive function by catechol-O-methyltransferase inhibition
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2012)

INVESTIGATION OF THE ROLE OF CATECHOL-O-METHYLTRANSFERASE(COMT) ON HIPPOCAMPUS-DEPENDENT BEHAVIOUR
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2010)

Computational Investigation of the Interplay of Substrate Positioning and Reactivity in Catechol O-Methyltransferase
द्वारा: Patra, Niladri, और अन्य
प्रकाशित: (2016)

Dissociable cost and benefit encoding of future rewards by mesolimbic dopamine.
द्वारा: Gan, J, और अन्य
प्रकाशित: (2010)

Action initiation shapes mesolimbic dopamine encoding of future rewards
द्वारा: Syed, ECJ, और अन्य
प्रकाशित: (2016)

An investigation of the effects of electroconvulsive shock on mesolimbic dopamine and amino acid transmitter system
द्वारा: Smith, S
प्रकाशित: (1995)

The Role of Catechol-O-Methyltransferase (COMT) in Modulating Hippocampal Dopaminergic Metabolism and Behaviour
द्वारा: Laatikainen, L, और अन्य
प्रकाशित: (2010)

CCK-8 modulation of mesolimbic dopamine: antagonism of amphetamine-stimulated behaviors.
द्वारा: Schneider, L, और अन्य
प्रकाशित: (1983)

Calculating utility: preclinical evidence for cost-benefit analysis by mesolimbic dopamine.
द्वारा: Phillips, P, और अन्य
प्रकाशित: (2007)

Mesolimbic dopamine encodes prediction errors in a state-dependent manner
द्वारा: Papageorgiou, GK, और अन्य
प्रकाशित: (2016)

Polymorphisms in the catechol-O-methyltransferase (COMT) gene influence plasma total homocysteine levels.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2008)

Investigating the presynaptic control of striatal dopamine release
द्वारा: Platt, N, और अन्य
प्रकाशित: (2012)

Expression of multiple catechol-o-methyltransferase (COMT) mRNA variants in human brain.
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2007)

Expression and functional impact of multiple catechol-o-methyltransferase (COMT) mRNA variants
द्वारा: Lane, T, और अन्य
प्रकाशित: (2007)

Detection and expression of multiple catechol-o-methyltransferase mRNA variants in human brain
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2007)

Learning about the distribution of rewards through dopamine and the basal ganglia pathways
द्वारा: Möller, M
प्रकाशित: (2021)

Association study between catechol-O-methyltransferase polymorphisms and uterine leiomyomas in a Japanese population.
द्वारा: Morikawa, J, और अन्य
प्रकाशित: (2008)

How Large Should the QM Region Be in QM/MM Calculations? The Case of Catechol O-Methyltransferase
द्वारा: Zhang, Jianyu, और अन्य
प्रकाशित: (2017)

Human plasma homocysteine levels are associated with the catechol-O-methyltransferase Val158Met polymorphism
द्वारा: Tunbridge, E, और अन्य
प्रकाशित: (2007)

Striatal GABA transporter regulation of dopamine release and dysfunction in Parkinsonian models
द्वारा: Roberts, BM
प्रकाशित: (2019)

COMT Val(158)Met genotype determines the direction of cognitive effects produced by catechol-O-methyltransferase inhibition.
द्वारा: Farrell, S, और अन्य
प्रकाशित: (2012)

Proceedings: Amphetamine and apomorphine responses in the rat after lesion of mesolimbic or striatal dopamine neurones.
द्वारा: Iversen, S, और अन्य
प्रकाशित: (1975)

Investigating circuits underlying acetylcholine-evoked striatal dopamine release in health and disease
द्वारा: Kosillo, P
प्रकाशित: (2014)

Association of the functional polymorphism in the catechol-O-methyltransferase gene with schizophrenia in the three ethnic groups of the Malaysian population
द्वारा: Wan, C.L., और अन्य
प्रकाशित: (2011)