Systems-level analysis of the mitotic entry switch

Entry into mitosis in eukaryotes depends on the activation of the Cyclin-dependent kinase 1 (Cdk1), which phosphorylates many mitotic protein substrates. Activation of Cdk1 requires formation of a complex with Cyclin B (CycB), which gradually rises in concentration during interphase. However, in mos...

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Bibliografische gegevens
Hoofdauteurs: Domingo Sananes, M, Maria Rosa Domingo Sananes
Andere auteurs: Novak, B
Formaat: Thesis
Taal:English
Gepubliceerd in: 2012
Onderwerpen: