Systems-level analysis of the mitotic entry switch
Entry into mitosis in eukaryotes depends on the activation of the Cyclin-dependent kinase 1 (Cdk1), which phosphorylates many mitotic protein substrates. Activation of Cdk1 requires formation of a complex with Cyclin B (CycB), which gradually rises in concentration during interphase. However, in mos...
| Main Authors: | , |
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| Other Authors: | |
| Format: | Thesis |
| Language: | English |
| Published: |
2012
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| Subjects: |