Control of immune-mediated disease of the central nervous system with monoclonal (CD4-specific) antibodies.

Control of immune-mediated disease of the central nervous system with monoclonal (CD4-specific) antibodies.

Chronic relapsing experimental allergic encephalomyelitis (CREAE) was induced in Biozzi AB/H (H-2dq1) mice by active sensitization with spinal cord antigens. A single i.p. injection of CD8-depleting (YTS169.4) monoclonal antibody (mAb) failed to affect the clinical course of CREAE when administered...

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Detalles Bibliográficos
Main Authors: O'Neill, J, Baker, D, Davison, A, Allen, S, Butter, C, Waldmann, H, Turk, J
Formato: Journal article
Idioma:English
Publicado: 1993

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