The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics

The pore domain of the nicotinic acetylcholine receptor: molecular modeling, pore dimensions, and electrostatics

The pore domain of the nicotinic acetylcholine receptor has been modeled as a bundle of five kinked M2 helices. Models were generated via molecular dynamics simulations incorporating restraints derived from 9-Å resolution cryoelectron microscopy data (Unwin, 1993; 1995), and from mutagenesis data th...

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Dettagli Bibliografici
Autori principali:	Sankararamakrishnan, R, Adcock, C, Sansom, M
Altri autori:	Biophysical Society
Natura:	Journal article
Lingua:	English
Pubblicazione:	Elsevier 1996
Soggetti:	Biophysics

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